Harikrushna Machines Private Limited

Harikrushna Machines Pvt. Ltd. (HMPL Sterile) presents an advanced Oral Liquid Manufacturing Plant designed to meet the growing demands of pharmaceutical companies. With production capacities ranging from 500 liters to 15,000 liters, this plant effectively handles the formulation and processing of various liquid oral medications. Its sophisticated design ensures precise mixing, homogenization, and temperature control, resulting in high-quality liquid products that meet stringent industry standards.

Equipped with a fully automated control system, the Oral Liquid Processing Plant minimizes manual intervention and enhances production efficiency. Operators can monitor critical parameters such as viscosity, temperature, and pH levels in real-time, ensuring consistent quality in every batch. The plant’s closed-circuit design reduces contamination risks, providing a hygienic environment for sensitive liquid formulations and improving overall product safety.

The versatility of the Oral Liquid Processing Plant allows it to accommodate a wide range of formulations, including syrups, suspensions, and solutions. Its scalable design makes it ideal for both small-scale startups and large-scale pharmaceutical manufacturers looking to expand their production capabilities. With a focus on user-friendly operation and easy maintenance, this plant is an excellent investment for businesses aiming to enhance their liquid processing efficiency.

HMPL Sterile's Oral Liquid Processing Plant combines affordability with superior functionality, making it a valuable addition to any pharmaceutical production line. Key features include an advanced PLC control system, customizable mixing tanks, and automated cleaning systems. These features ensure efficient operation while maintaining product integrity, all at a competitive price point that delivers excellent value for manufacturers.

Harikrushna Machines Pvt. Ltd. (HMPL Sterile) presents an advanced Oral Liquid Manufacturing Plant designed to meet the growing demands of pharmaceutical companies. With production capacities ranging from 500 liters to 15,000 liters, this plant effectively handles the formulation and processing of various liquid oral medications. Its sophisticated design ensures precise mixing, homogenization, and temperature control, resulting in high-quality liquid products that meet stringent industry standards.

Equipped with a fully automated control system, the Oral Liquid Processing Plant minimizes manual intervention and enhances production efficiency. Operators can monitor critical parameters such as viscosity, temperature, and pH levels in real-time, ensuring consistent quality in every batch. The plant’s closed-circuit design reduces contamination risks, providing a hygienic environment for sensitive liquid formulations and improving overall product safety.

The versatility of the Oral Liquid Processing Plant allows it to accommodate a wide range of formulations, including syrups, suspensions, and solutions. Its scalable design makes it ideal for both small-scale startups and large-scale pharmaceutical manufacturers looking to expand their production capabilities. With a focus on user-friendly operation and easy maintenance, this plant is an excellent investment for businesses aiming to enhance their liquid processing efficiency.

HMPL Sterile's Oral Liquid Processing Plant combines affordability with superior functionality, making it a valuable addition to any pharmaceutical production line. Key features include an advanced PLC control system, customizable mixing tanks, and automated cleaning systems. These features ensure efficient operation while maintaining product integrity, all at a competitive price point that delivers excellent value for manufacturers.

Harikrushna Machines Pvt. Ltd. (HMPL Sterile) presents an advanced Oral Liquid Manufacturing Plant designed to meet the growing demands of pharmaceutical companies. With production capacities ranging from 500 liters to 15,000 liters, this plant effectively handles the formulation and processing of various liquid oral medications. Its sophisticated design ensures precise mixing, homogenization, and temperature control, resulting in high-quality liquid products that meet stringent industry standards.
Equipped with a fully automated control system, the Oral Liquid Processing Plant minimizes manual intervention and enhances production efficiency. Operators can monitor critical parameters such as viscosity, temperature, and pH levels in real-time, ensuring consistent quality in every batch. The plant’s closed-circuit design reduces contamination risks, providing a hygienic environment for sensitive liquid formulations and improving overall product safety.
The versatility of the Oral Liquid Processing Plant allows it to accommodate a wide range of formulations, including syrups, suspensions, and solutions. Its scalable design makes it ideal for both small-scale startups and large-scale pharmaceutical manufacturers looking to expand their production capabilities. With a focus on user-friendly operation and easy maintenance, this plant is an excellent investment for businesses aiming to enhance their liquid processing efficiency.
HMPL Sterile's Oral Liquid Processing Plant combines affordability with superior functionality, making it a valuable addition to any pharmaceutical production line. Key features include an advanced PLC control system, customizable mixing tanks, and automated cleaning systems. These features ensure efficient operation while maintaining product integrity, all at a competitive price point that delivers excellent value for manufacturers.

Harikrushna Machines Pvt. Ltd. (HMPL Sterile) presents an advanced Oral Liquid Manufacturing Plant designed to meet the growing demands of pharmaceutical companies. With production capacities ranging from 500 liters to 15,000 liters, this plant effectively handles the formulation and processing of various liquid oral medications. Its sophisticated design ensures precise mixing, homogenization, and temperature control, resulting in high-quality liquid products that meet stringent industry standards.

Equipped with a fully automated control system, the Oral Liquid Processing Plant minimizes manual intervention and enhances production efficiency. Operators can monitor critical parameters such as viscosity, temperature, and pH levels in real-time, ensuring consistent quality in every batch. The plant’s closed-circuit design reduces contamination risks, providing a hygienic environment for sensitive liquid formulations and improving overall product safety.

The versatility of the Oral Liquid Processing Plant allows it to accommodate a wide range of formulations, including syrups, suspensions, and solutions. Its scalable design makes it ideal for both small-scale startups and large-scale pharmaceutical manufacturers looking to expand their production capabilities. With a focus on user-friendly operation and easy maintenance, this plant is an excellent investment for businesses aiming to enhance their liquid processing efficiency.

HMPL Sterile's Oral Liquid Processing Plant combines affordability with superior functionality, making it a valuable addition to any pharmaceutical production line. Key features include an advanced PLC control system, customizable mixing tanks, and automated cleaning systems. These features ensure efficient operation while maintaining product integrity, all at a competitive price point that delivers excellent value for manufacturers.

Harikrushna Machines Pvt. Ltd. (HMPL Sterile) presents an advanced Oral Liquid Manufacturing Plant designed to meet the growing demands of pharmaceutical companies. With production capacities ranging from 500 liters to 15,000 liters, this plant effectively handles the formulation and processing of various liquid oral medications. Its sophisticated design ensures precise mixing, homogenization, and temperature control, resulting in high-quality liquid products that meet stringent industry standards.

Equipped with a fully automated control system, the Oral Liquid Processing Plant minimizes manual intervention and enhances production efficiency. Operators can monitor critical parameters such as viscosity, temperature, and pH levels in real-time, ensuring consistent quality in every batch. The plant’s closed-circuit design reduces contamination risks, providing a hygienic environment for sensitive liquid formulations and improving overall product safety.

The versatility of the Oral Liquid Processing Plant allows it to accommodate a wide range of formulations, including syrups, suspensions, and solutions. Its scalable design makes it ideal for both small-scale startups and large-scale pharmaceutical manufacturers looking to expand their production capabilities. With a focus on user-friendly operation and easy maintenance, this plant is an excellent investment for businesses aiming to enhance their liquid processing efficiency.

HMPL Sterile's Oral Liquid Processing Plant combines affordability with superior functionality, making it a valuable addition to any pharmaceutical production line. Key features include an advanced PLC control system, customizable mixing tanks, and automated cleaning systems. These features ensure efficient operation while maintaining product integrity, all at a competitive price point that delivers excellent value for manufacturers.

Harikrushna Machines Pvt. Ltd. introduces the Pet Bottle Filling And Capping Machine/ Automatic Monoblock Liquid Filling, Inner Plugging, and Screw Capping Machine, a versatile and innovative solution for seamless pharmaceutical packaging. Designed to integrate three critical processes—liquid filling, inner plugging, and capping—this machine enhances productivity and accuracy while meeting the demands of modern pharmaceutical manufacturing. With a remarkable output speed of up to 200 bottles per minute, it is ideal for packaging liquid bottles, eye and ear drop bottles, vials, and nasal sprays, ensuring precision and compliance with GMP standards.

Built with advanced technology and a robust SS 316L and SS 304 structure, the Monoblock Filling Machine guarantees a vibration-free operation and exceptional durability. Its cutting-edge features, including a rotary motion filling system, electromagnetic vibrators, and co-eccentric nozzles, deliver precise and efficient filling. The machine’s 7” touchscreen HMI with PLC programming ensures user-friendly operation, offering real-time fault detection and easy changeovers. Additionally, features like the nitrogen purging option, CIP/SIP-compatible pharma-grade silicon tubes, and LAF-equipped clean-air environment highlight its focus on quality and hygiene.

As an ISO 9001:2015 and CE-certified manufacturer, Harikrushna Machines Pvt. Ltd. ensures superior engineering and exceptional after-sales support. Whether you are a start-up or a large-scale business, this Monoblock Filling Machine is your trusted partner in achieving consistent results, reduced downtime, and streamlined operations. Its versatility and customizable options make it the perfect choice for businesses aiming to elevate their packaging efficiency.

Harikrushna Machines Pvt. Ltd. takes pride in delivering state-of-the-art Automatic Nasal Spray Filling Machine designed to meet the rigorous demands of the pharmaceutical industry. Our cutting-edge machine offers unmatched versatility, capable of filling nasal spray bottles ranging from 5 ml to 30 ml with an impressive output speed of up to 200 bottles per minute. Built with advanced automation technology, this machine ensures precision in every fill while integrating automated crimping for hands-free, efficient operations. From small-scale production to high-volume requirements, our Nasal Spray Filling Machine guarantees consistent performance and superior product integrity.

Backed by over 25 years of industry expertise, Harikrushna Machines Pvt. Ltd. stands as an ISO 9001:2015 and CE-certified manufacturer trusted by customers in more than 60 countries. Our commitment to customization ensures that the Nasal Spray Packaging Line is tailored to specific client needs, featuring innovative elements like star wheel sets, toughened glass cabinets, and laminar airflow units for maximum cleanliness and efficiency. Designed with compliance and reliability in mind, the machine supports 21 CFR standards, making it a robust solution for the modern pharmaceutical market.

With a focus on excellence and global reach, we have successfully installed 12,500+ machines worldwide, offering comprehensive packaging solutions for diverse industries. Whether you seek precision filling, streamlined operations, or unparalleled versatility, Harikrushna Machines Pvt. Ltd.’s Nasal Spray Filling Machine embodies the perfect synergy of innovation and reliability.

Depyrogenation Tunnels | Sterilization Tunnels Manufacturer and Exporter in IndiaDepyrogenation tunnels, also known as dry heat sterilization tunnels or hot air tunnels, are specialized equipment used in the pharmaceutical and biotechnology industries to remove pyrogens from vials, ampoules, and other containers used in the manufacturing of sterile products.

Sterilization and Depyrogenation Tunnel by Harikrushna Machines Pvt. Ltd. (HMPL Sterile). Harikrushna Machines (HMPL Sterile) offers state-of-art Pharmaceutical Sterilization & Depyrogenation Tunnel for drying, sterilization & depyrogenation of glass containers such as ampoules, vials, injection and infusion bottles, cartridges or syringes.

Key Features and Principles:High Temperature:Controlled Airflow:Conveyor System:Validation:Monitoring and Control:Materials Compatibility:
Tunnel for drying, sterilization and depyrogenationHarikrushna Machines Pvt. Ltd. (HMPL Sterile) offers a diverse array of sterilization tunnels, delivering versatile solutions for the efficient and sustainable treatment of various glass container types. Utilizing dry heat sterilization enables you to attain consistent treatment quality while optimizing energy consumption. Whether you are packaging liquid pharmaceuticals into ampoules, vials, injection and infusion bottles, cartridges, or syringes, ensuring the dependable sterilization of containers plays a crucial role in enhancing product safety.

Vial Sterilization Tunnel:A vial sterilization tunnel is a specialized piece of equipment used in pharmaceutical manufacturing.It ensure the sterility of vials before they are filled with drugs or other sterile substances.This tunnel employs a controlled environment, typically utilizing dry heat or other sterilization methods.To eliminate or reduce microbial contaminants, ensuring the integrity and safety of the final pharmaceutical product.

Harikrushna Machines offers state-of-art Pharmaceutical Sterilizing Depyrogenation Tunnel for drying, sterilization & depyrogenation of glass containers such as ampoules, vials, injection and infusion bottles, cartridges or syringes.

Depyrogenation Tunnels | Sterilization Tunnels Manufacturer and Exporter in IndiaDepyrogenation tunnels, also known as dry heat sterilization tunnels or hot air tunnels, are specialized equipment used in the pharmaceutical and biotechnology industries to remove pyrogens from vials, ampoules, and other containers used in the manufacturing of sterile products.

Sterilization and Depyrogenation Tunnel by Harikrushna Machines Pvt. Ltd. (HMPL Sterile)Harikrushna Machines (HMPL Sterile) offers state-of-art Pharmaceutical Sterilization & Depyrogenation Tunnel for drying, sterilization & depyrogenation of glass containers such as ampoules, vials, injection and infusion bottles, cartridges or syringes.

Key Features and Principles:High Temperature:Controlled Airflow:Conveyor System:Validation:Monitoring and Control:Materials Compatibility:
Tunnel for drying, sterilization and depyrogenationHarikrushna Machines Pvt. Ltd. (HMPL Sterile) offers a diverse array of sterilization tunnels, delivering versatile solutions for the efficient and sustainable treatment of various glass container types. Utilizing dry heat sterilization enables you to attain consistent treatment quality while optimizing energy consumption. Whether you are packaging liquid pharmaceuticals into ampoules, vials, injection and infusion bottles, cartridges, or syringes, ensuring the dependable sterilization of containers plays a crucial role in enhancing product safety.

Vial Sterilization Tunnel:A vial sterilization tunnel is a specialized piece of equipment used in pharmaceutical manufacturing.It ensure the sterility of vials before they are filled with drugs or other sterile substances.This tunnel employs a controlled environment, typically utilizing dry heat or other sterilization methods.To eliminate or reduce microbial contaminants, ensuring the integrity and safety of the final pharmaceutical product.

Depyrogenation Tunnels | Sterilization Tunnels Manufacturer and Exporter in IndiaDepyrogenation tunnels, also known as dry heat sterilization tunnels or hot air tunnels, are specialized equipment used in the pharmaceutical and biotechnology industries to remove pyrogens from vials, ampoules, and other containers used in the manufacturing of sterile products.

Sterilization and Depyrogenation Tunnel by Harikrushna Machines Pvt. Ltd. (HMPL Sterile). Harikrushna Machines (HMPL Sterile) offers state-of-art Pharmaceutical Sterilization & Depyrogenation Tunnel for drying, sterilization & depyrogenation of glass containers such as ampoules, vials, injection and infusion bottles, cartridges or syringes.

Key Features and Principles:High Temperature:Controlled Airflow:Conveyor System:Validation:Monitoring and Control:Materials Compatibility:
Tunnel for drying, sterilization and depyrogenationHarikrushna Machines Pvt. Ltd. (HMPL Sterile) offers a diverse array of sterilization tunnels, delivering versatile solutions for the efficient and sustainable treatment of various glass container types. Utilizing dry heat sterilization enables you to attain consistent treatment quality while optimizing energy consumption. Whether you are packaging liquid pharmaceuticals into ampoules, vials, injection and infusion bottles, cartridges, or syringes, ensuring the dependable sterilization of containers plays a crucial role in enhancing product safety.

Vial Sterilization Tunnel:A vial sterilization tunnel is a specialized piece of equipment used in pharmaceutical manufacturing.It ensure the sterility of vials before they are filled with drugs or other sterile substances.This tunnel employs a controlled environment, typically utilizing dry heat or other sterilization methods.To eliminate or reduce microbial contaminants, ensuring the integrity and safety of the final pharmaceutical product.

Depyrogenation Tunnels | Sterilization Tunnels Manufacturer and Exporter in IndiaDepyrogenation tunnels, also known as dry heat sterilization tunnels or hot air tunnels, are specialized equipment used in the pharmaceutical and biotechnology industries to remove pyrogens from vials, ampoules, and other containers used in the manufacturing of sterile products.

Sterilization and Depyrogenation Tunnel by Harikrushna Machines Pvt. Ltd. (HMPL Sterile). Harikrushna Machines (HMPL Sterile) offers state-of-art Pharmaceutical Sterilization & Depyrogenation Tunnel for drying, sterilization & depyrogenation of glass containers such as ampoules, vials, injection and infusion bottles, cartridges or syringes.

Key Features and Principles:High Temperature:Controlled Airflow:Conveyor System:Validation:Monitoring and Control:Materials Compatibility:
Tunnel for drying, sterilization and depyrogenationHarikrushna Machines Pvt. Ltd. (HMPL Sterile) offers a diverse array of sterilization tunnels, delivering versatile solutions for the efficient and sustainable treatment of various glass container types. Utilizing dry heat sterilization enables you to attain consistent treatment quality while optimizing energy consumption. Whether you are packaging liquid pharmaceuticals into ampoules, vials, injection and infusion bottles, cartridges, or syringes, ensuring the dependable sterilization of containers plays a crucial role in enhancing product safety.

Vial Sterilization Tunnel:A vial sterilization tunnel is a specialized piece of equipment used in pharmaceutical manufacturing.It ensure the sterility of vials before they are filled with drugs or other sterile substances.This tunnel employs a controlled environment, typically utilizing dry heat or other sterilization methods.To eliminate or reduce microbial contaminants, ensuring the integrity and safety of the final pharmaceutical product.

Depyrogenation Tunnels | Sterilization Tunnels Manufacturer and Exporter in IndiaDepyrogenation tunnels, also known as dry heat sterilization tunnels or hot air tunnels, are specialized equipment used in the pharmaceutical and biotechnology industries to remove pyrogens from vials, ampoules, and other containers used in the manufacturing of sterile products.

Sterilization and Depyrogenation Tunnel by Harikrushna Machines Pvt. Ltd. (HMPL Sterile). Harikrushna Machines (HMPL Sterile) offers state-of-art Pharmaceutical Sterilization & Depyrogenation Tunnel for drying, sterilization & depyrogenation of glass containers such as ampoules, vials, injection and infusion bottles, cartridges or syringes.

Key Features and Principles:High Temperature:Controlled Airflow:Conveyor System:Validation:Monitoring and Control:Materials Compatibility:
Tunnel for drying, sterilization and depyrogenationHarikrushna Machines Pvt. Ltd. (HMPL Sterile) offers a diverse array of sterilization tunnels, delivering versatile solutions for the efficient and sustainable treatment of various glass container types. Utilizing dry heat sterilization enables you to attain consistent treatment quality while optimizing energy consumption. Whether you are packaging liquid pharmaceuticals into ampoules, vials, injection and infusion bottles, cartridges, or syringes, ensuring the dependable sterilization of containers plays a crucial role in enhancing product safety.

Vial Sterilization Tunnel:A vial sterilization tunnel is a specialized piece of equipment used in pharmaceutical manufacturing.It ensure the sterility of vials before they are filled with drugs or other sterile substances.This tunnel employs a controlled environment, typically utilizing dry heat or other sterilization methods.To eliminate or reduce microbial contaminants, ensuring the integrity and safety of the final pharmaceutical product.

Depyrogenation Tunnels | Sterilization Tunnels Manufacturer and Exporter in IndiaDepyrogenation tunnels, also known as dry heat sterilization tunnels or hot air tunnels, are specialized equipment used in the pharmaceutical and biotechnology industries to remove pyrogens from vials, ampoules, and other containers used in the manufacturing of sterile products.

Sterilization and Depyrogenation Tunnel by Harikrushna Machines Pvt. Ltd. (HMPL Sterile). Harikrushna Machines (HMPL Sterile) offers state-of-art Pharmaceutical Sterilization & Depyrogenation Tunnel for drying, sterilization & depyrogenation of glass containers such as ampoules, vials, injection and infusion bottles, cartridges or syringes.

Key Features and Principles:High Temperature:Controlled Airflow:Conveyor System:Validation:Monitoring and Control:Materials Compatibility:
Tunnel for drying, sterilization and depyrogenationHarikrushna Machines Pvt. Ltd. (HMPL Sterile) offers a diverse array of sterilization tunnels, delivering versatile solutions for the efficient and sustainable treatment of various glass container types. Utilizing dry heat sterilization enables you to attain consistent treatment quality while optimizing energy consumption. Whether you are packaging liquid pharmaceuticals into ampoules, vials, injection and infusion bottles, cartridges, or syringes, ensuring the dependable sterilization of containers plays a crucial role in enhancing product safety.

Vial Sterilization Tunnel:A vial sterilization tunnel is a specialized piece of equipment used in pharmaceutical manufacturing.It ensure the sterility of vials before they are filled with drugs or other sterile substances.This tunnel employs a controlled environment, typically utilizing dry heat or other sterilization methods.To eliminate or reduce microbial contaminants, ensuring the integrity and safety of the final pharmaceutical product.

Depyrogenation Tunnels | Sterilization Tunnels Manufacturer and Exporter in IndiaDepyrogenation tunnels, also known as dry heat sterilization tunnels or hot air tunnels, are specialized equipment used in the pharmaceutical and biotechnology industries to remove pyrogens from vials, ampoules, and other containers used in the manufacturing of sterile products.

Sterilization and Depyrogenation Tunnel by Harikrushna Machines Pvt. Ltd. (HMPL Sterile). Harikrushna Machines (HMPL Sterile) offers state-of-art Pharmaceutical Sterilization & Depyrogenation Tunnel for drying, sterilization & depyrogenation of glass containers such as ampoules, vials, injection and infusion bottles, cartridges or syringes.

Key Features and Principles:High Temperature:Controlled Airflow:Conveyor System:Validation:Monitoring and Control:Materials Compatibility:
Tunnel for drying, sterilization and depyrogenationHarikrushna Machines Pvt. Ltd. (HMPL Sterile) offers a diverse array of sterilization tunnels, delivering versatile solutions for the efficient and sustainable treatment of various glass container types. Utilizing dry heat sterilization enables you to attain consistent treatment quality while optimizing energy consumption. Whether you are packaging liquid pharmaceuticals into ampoules, vials, injection and infusion bottles, cartridges, or syringes, ensuring the dependable sterilization of containers plays a crucial role in enhancing product safety.

Vial Sterilization Tunnel:A vial sterilization tunnel is a specialized piece of equipment used in pharmaceutical manufacturing.It ensure the sterility of vials before they are filled with drugs or other sterile substances.This tunnel employs a controlled environment, typically utilizing dry heat or other sterilization methods.To eliminate or reduce microbial contaminants, ensuring the integrity and safety of the final pharmaceutical product.

Sterilization Tunnel Manufacturer and Exporter in India

Sterilization Tunnel, also known as dry heat sterilization tunnel or hot air tunnel, is specialized equipment used in the pharmaceutical and biotechnology industries to remove pyrogens from vials, ampoules, and other containers used in the manufacturing of sterile products.

Sterilization and Depyrogenation Tunnel by Harikrushna Machines Pvt. Ltd. (HMPL Sterile)

Harikrushna Machines (HMPL Sterile) offers state-of-art Pharmaceutical Sterilization & Depyrogenation Tunnel for drying, sterilization & depyrogenation of glass containers such as ampoules, vials, injection and infusion bottles, cartridges or syringes. Key Features and Principles:

1. High Temperature:
2. Controlled Airflow:
3. Conveyor System:
4. Validation:
5. Monitoring and Control:
6. Materials Compatibility:

Tunnel for drying, sterilization and depyrogenation

Harikrushna Machines Pvt. Ltd. (HMPL Sterile) offers a diverse array of sterilization tunnels, delivering versatile solutions for the efficient and sustainable treatment of various glass container types. Utilizing dry heat sterilization enables you to attain consistent treatment quality while optimizing energy consumption. Whether you are packaging liquid pharmaceuticals into ampoules, vials, injection and infusion bottles, cartridges, or syringes, ensuring the dependable sterilization of containers plays a crucial role in enhancing product safety.

Vial Sterilization Tunnel:

• A vial sterilization tunnel is a specialized piece of equipment used in pharmaceutical manufacturing.
• It ensures the sterility of vials before they are filled with drugs or other sterile substances.
• This tunnel employs a controlled environment, typically utilizing dry heat or other sterilization methods.
• To eliminate or reduce microbial contaminants, ensuring the integrity and safety of the final pharmaceutical product.

Pharmaceutical Sterilizing Tunnel Manufacturer and Exporter in India

Pharmaceutical Sterilizing Tunnel, also known as dry heat sterilization tunnel or hot air tunnel, is specialized equipment used in the pharmaceutical and biotechnology industries to remove pyrogens from vials, ampoules, and other containers used in the manufacturing of sterile products.

Sterilization and Depyrogenation Tunnel by Harikrushna Machines Pvt. Ltd. (HMPL Sterile)

Harikrushna Machines (HMPL Sterile) offers state-of-art Pharmaceutical Sterilization & Depyrogenation Tunnel for drying, sterilization & depyrogenation of glass containers such as ampoules, vials, injection and infusion bottles, cartridges or syringes. Key Features and Principles:

1. High Temperature:
2. Controlled Airflow:
3. Conveyor System:
4. Validation:
5. Monitoring and Control:
6. Materials Compatibility:

Tunnel for drying, sterilization and depyrogenation

Harikrushna Machines Pvt. Ltd. (HMPL Sterile) offers a diverse array of sterilization tunnels, delivering versatile solutions for the efficient and sustainable treatment of various glass container types. Utilizing dry heat sterilization enables you to attain consistent treatment quality while optimizing energy consumption. Whether you are packaging liquid pharmaceuticals into ampoules, vials, injection and infusion bottles, cartridges, or syringes, ensuring the dependable sterilization of containers plays a crucial role in enhancing product safety.

Vial Sterilization Tunnel:

• A vial sterilization tunnel is a specialized piece of equipment used in pharmaceutical manufacturing.
• It ensures the sterility of vials before they are filled with drugs or other sterile substances.
• This tunnel employs a controlled environment, typically utilizing dry heat or other sterilization methods.
• To eliminate or reduce microbial contaminants, ensuring the integrity and safety of the final pharmaceutical product.

Harikrushna Machines Pvt. Ltd. (HMPL Sterile) presents an advanced Oral Liquid Manufacturing Plant designed to meet the growing demands of pharmaceutical companies. With production capacities ranging from 500 liters to 15,000 liters, this plant effectively handles the formulation and processing of various liquid oral medications. Its sophisticated design ensures precise mixing, homogenization, and temperature control, resulting in high-quality liquid products that meet stringent industry standards.

Equipped with a fully automated control system, the Oral Liquid Processing Plant minimizes manual intervention and enhances production efficiency. Operators can monitor critical parameters such as viscosity, temperature, and pH levels in real-time, ensuring consistent quality in every batch. The plant’s closed-circuit design reduces contamination risks, providing a hygienic environment for sensitive liquid formulations and improving overall product safety.

The versatility of the Oral Liquid Processing Plant allows it to accommodate a wide range of formulations, including syrups, suspensions, and solutions. Its scalable design makes it ideal for both small-scale startups and large-scale pharmaceutical manufacturers looking to expand their production capabilities. With a focus on user-friendly operation and easy maintenance, this plant is an excellent investment for businesses aiming to enhance their liquid processing efficiency.

HMPL Sterile's Oral Liquid Processing Plant combines affordability with superior functionality, making it a valuable addition to any pharmaceutical production line. Key features include an advanced PLC control system, customizable mixing tanks, and automated cleaning systems. These features ensure efficient operation while maintaining product integrity, all at a competitive price point that delivers excellent value for manufacturers.

The Automated Combo Filling and Closing System from HMPL Sterile is revolutionizing pharmaceutical packaging with its unparalleled versatility and cutting-edge design. Seamlessly handling syringes, vials, and cartridges in a single system without changeover downtime, this 3-in-1 solution is a game-changer for efficiency and adaptability. Featuring robotic-level output, the system ensures high-speed filling, stoppering, and sealing, delivering unmatched precision and reliability. With its automated TYVEK lid application and linear removal system, the process remains sterile and entirely hands-free, meeting the stringent demands of modern cleanroom environments. Its compact, space-saving design optimizes floor plans, fitting effortlessly into GMP-compliant facilities while maintaining full-scale performance.

Engineered for the future of pharma, this system offers servo-based precision dosing, modular scalability, and seamless integration with existing production lines. Designed for 21 CFR Part 11 compliance, it ensures adherence to global regulatory standards while accommodating bagged stoppers and nested formats with ease. At HMPL Sterile, innovation meets agility, empowering pharmaceutical manufacturers to scale faster, enhance compliance, and gain a competitive edge in the global market. Choose a partner that blends robotic precision with engineering excellence, and transform your packaging processes with confidence.

The Liquid Vial Filling Machine consist of a main structure covered with SS cabinet safety acrylic cover, laminar air flow, in-feed turntable Machine, peristaltic pump filling Machine, Delrin Slate conveyor, outfeed turn table, vibrator bowl & chute for rubber stopper, pneumatic components and electrical panel, AC Drive, PLC & HMI.  

• Model: HMPL-PRE-VFB
• Output Speed: 30 to 100 Vials/Minute (Depend upon nature of liquid & size of vials)

Key Features:

• The machine is made compact & versatile as per GMP norms.
• The structure is made out of MS cladding with SS 304.
• Rigid vibration-free construction for trouble-free performance.
• The contact parts such as filling nozzle, bung disc are made of SS316 L.
• The Pharma grade silicon tubes are used for filling & CIP/SIP.
• Easy to clean the base of the machine.
• There is a special feature called PRIME which is useful to suck the filling material from storage tank to nozzle end very quickly. Moreover, this facility is useful to clean the filling line (silicon tubes) as well as filling peristaltic pump in both directions.
• The machine has a facility of using PRIME function for all the peristaltic pumps together or individual peristaltic pumps also.
• The process of filling is done by specially designed filling peristaltic pump which can serve the purpose of CIP & SIP.
• Individual pumps can be adjusted & calibrated for the desired volume – by use of easy to operate PLC.
• Oil-based material can also be run easily without dripping because of specially designed peristaltic pump with the facility of suck back.
• Each filling head can work independently & hence the machine works continuously without sacrificing major production.
• No change parts are required for different size of vials as well as different filling volume.
• There is a very less product change over time due to very less usage of mechanical parts such as syringe set, Teflon seal, gear & chain etc.
• Easy to operate PLC for any kind of volume adjustment or speed adjustment.
• Synchronized filling system for smooth filling purpose.
• Specially designed bung oriental bowl & discharge chute with in-built vibrator. The bung oriental bowl & chute are Teflon coated for use of wet bungs.
• Bungs are held in the specially designed vacuum bung hold disc & the same disc discharge the bung uniformly on the vial. The bung pressing roller presses the bungs uniformly.
• The same Rubber bunging machine assembly can also be utilized for half stoppering.
• For different heights of vials, the whole assembly can be moved upwards & downwards.
• Alarm alerts through PLC for “No Vial, Machine Stop” & No Vial, No Bung”.
• Production counter is given with password protection for daily track report and planning for the same.
• The faults can be detected on the PLC touch screen HMI and can be attended easily for the same.
• The machine is supplied with isolated power supply to avoid the adverse effect of electric supply.
• The output speed can be appeared on HMI screen and adjust the same as per appropriate requirements.
• Very less mechanical adjustment required due to the special design.
• User-friendly and very less maintenance required.
• Nitrogen facility (Pre or Post) can be provided as an (OPTIONAL).
• Unique design of rolling conveyor.

The Rotary Vial Washing Machine washes vials with minimal contact between machine parts and the vial. Our vial washing equipment effectively washes various sizes of vials with the assistance of changing parts.
Harikrushna Machines Pvt. Ltd. (HMPL Sterile) is an ISO 9001:2015 and CE-certified pharmaceutical packaging machinery manufacturer and exporter in India. The pharmaceutical, veterinary, and biotech industries widely use our system. The specially designed Gripper System holds the vial from the neck and inverts it until the washing operation. Again After washing, the machine releases the vial on the out-feed feed screw system in a vertical position, ensuring positive wash vials.

Ensuring Product Quality and Safety:Vial Washing Machines remove particles and residues from vials used for pharmaceutical products. This process is crucial for maintaining the integrity, purity, and safety of the drugs. Clean vials reduce the risk of contamination and ensure that medications are safe for patient use.
Compliance with Regulatory Standards:Pharmaceutical manufacturing is subject to stringent regulations and quality standards imposed by regulatory authorities. Our vial washing system meets Good Manufacturing Practices (GMP) needs and ensures compliance with cleanliness standards.
Prevention of Cross-Contamination:Vial washing machines help prevent cross-contamination.
Maintaining Product Efficacy:Vial Cleaning Machine clean vials are essential for maintaining the efficacy and stability of pharmaceutical products. Contaminants or residues left in vials can interact with drug formulations, affecting their shelf life.
Cost-Efficiency and Productivity:Manual vial washing is time-consuming, while automated  external vial washing machines offer significant cost savings and increased productivity.

Enhanced Reputation and Customer Trust:Pharmaceutical companies that invest in high-quality vial washing technology demonstrate their commitment to product quality, safety, and patient well-being. The suitability of a specific type of vial washer for an application relies on factors such as the size and shape of the vials, the desired cleaning level, and the production speed. We also provide customized vial washing systems tailored to customer requirements with reasonable cost.
Model & Output Speed:

• HMPL-RVW-120 - 120 Vials/ Minute
• HMPL-RVW-240 - 240 Vials/ Minute
• HMPL-RVW-300 - 300 Vials/ Minute

Key Features:

• As per GMP norms machine model.
• Basic Machine will be provided with one set of change parts suitable for 5/10ml Vial.
• Inbuilt In Feed Turn Table Machine Of 36″ Dia.
• Individual Solenoid Valve for Wash Media Application.
• 3 Nos. SS Centrifugal Pumps of Grundfos Make.
• 3 Nos. SS 316 L Tanks
• 1 No. Each For DM Water & Re-circulation Water, WFI Water & Compressed Air Can Be Directly From Loop Connection.
• 4 Nos. Of Glycerin Filled Pressure Gauges – Micro Make.
• 4 Nos. Of SS316 L Filter Housing Of Code -7 with Its Nylon Cartridges. (Own Make Housing & Grace Make Cartridges)
• Gear Box & Motors – Bonfiglioli/Rotomotive Make. (Machine & Conveyor)
• A. C. Frequency Drive For Speed Control. (Delta Make)
• Emergency Switch is provided on Both End. (In Feed & Out Feed)

Machine Brief:

• Machine is Suitable for 2 ml to 100 ml vials (with help of change parts).
• In Feed Worm, In Feed and Out Feed Star Wheel and Back Guide Set
• Air Purging System For Removal Of Water From Needles Piping -(4 Nos. Solenoid Valve For With Plc Module For Auto Flushing (purging) After Production)
• Vapour Exhaust Port

The Syringe Filling Machine consisting of the main structure covered polycarbonate cabinet and SS 304 pipe, laminar airflow, filling head with individual servo motor, out-feed collection tray, vacuum system, pneumatic components, and electrical panel, AC Drive, PLC & HMI. Syringe Filling Machine & Stoppering Machine loaded on Stainless Steel in-feed hopper. A prefilled syringe manufacturing process machine tray can directly be loaded onto the PFS machine. Duly filled & stoppered syringes delivered on outfeed collection tray without hand touch.

• Model: ACCUFILLCOMBO-PFS
• Output Speed: Up to 100 PFS per minute @ 1 ml
  (Output may vary based on nature of the filling substance and volume)

Key Features:

• The machine is manufactured or developed accordance with GMP standards.
• The structure is made of SS 304 or cladded with SS 304.
• Rigid vibration free construction for trouble free performance.
• Machine without-feed trays for collection of syringe tub.
• All contact parts SS 316L and non-contact parts are SS 304.
• Machine suitable for different syringe size with help of change part and depends on characteristic of liquid.
• Servo with syringes synchronized system for filling Accuracy.
• Filling volume set with touch screen HMI.
• Pneumatically controlled Stoppering mechanism.
• Very easy & accurate electronic based volume setting of different pre-fill syringes.
• Zero Dripping filling stations.
• Diving system with the design of timer belt and Stepper Motor/pneumatic Control which has no Vibration and very
• smooth kind of filling, filling material must be Fill Centrally in the Syringe.
• Design of Nozzles and adjustment of flow rate is very useful for filling with minimum Air Bubble / foaming in
• the Syringes.
• Low air machine stop sensor.
• LAF stop machine stop sensor.
• Door interlocking system.
• A suitable expandable PLC with programming & 7” colour touch screen HMI.
• The Pharma grade silicon tubes are used for filling & CIP/SIP.
• There is a very less product change over time due to very less usage of mechanical parts.
• All liquid contact parts easily removable for cleaning and sterilization purpose.
• Machine with LAF which can maintain class 100 condition (OPTIONAL).
• Co eccentric nozzles for quick filling of liquids.
• For different heights of syringes, the whole assembly can be moved upwards & downwards.
• Production counter is given with password protection for daily track report.
• The faults can be detected on the PLC touch screen HMI and can be attended easily.
• The output speed can be appeared on HMI screen.
• Very less mechanical adjustment required due to the special design.
• User friendly and very less maintenance required.
• NITROGEN FLUSHING SYSTEM [OPTIONAL]: The filling unit has an inbuilt system for nitrogen flush. The unique dual
• filling nozzle flushes nitrogen before filling followed by filling operation.
• Most reliable & proven mechanical components such as pneumatics & CE certified electrical/electronic such as AC
• motor, AC Drives, PLC & HMI Touch screen, safety interlock & Sensors, MCB’s, relay etc.

The Dental Cartridge Filling Sealing Machine consisting of the main structure covered polycarbonate cabinet and SS 304 pipe, laminar airflow, filling head with individual servo motor, out-feed collection tray, vacuum system, pneumatic components, and electrical panel, AC Drive, PLC & HMI. Syringe Filling Machine & Stoppering Machine loaded on Stainless Steel in-feed hopper. A prefilled syringe manufacturing process machine tray can directly be loaded onto the PFS machine. Duly filled & stoppered syringes delivered on outfeed collection tray without hand touch.

• Model: ACCUFILLCOMBO-PFS
• Output Speed: Up to 100 PFS per minute @ 1 ml
  (Output may vary based on nature of the filling substance and volume)

Key Features:

• The machine is manufactured or developed accordance with GMP standards.
• The structure is made of SS 304 or cladded with SS 304.
• Rigid vibration free construction for trouble free performance.
• Machine without-feed trays for collection of syringe tub.
• All contact parts SS 316L and non-contact parts are SS 304.
• Machine suitable for different syringe size with help of change part and depends on characteristic of liquid.
• Servo with syringes synchronized system for filling Accuracy.
• Filling volume set with touch screen HMI.
• Pneumatically controlled Stoppering mechanism.
• Very easy & accurate electronic based volume setting of different pre-fill syringes.
• Zero Dripping filling stations.
• Diving system with the design of timer belt and Stepper Motor/pneumatic Control which has no Vibration and very
• smooth kind of filling, filling material must be Fill Centrally in the Syringe.
• Design of Nozzles and adjustment of flow rate is very useful for filling with minimum Air Bubble / foaming in
• the Syringes.
• Low air machine stop sensor.
• LAF stop machine stop sensor.
• Door interlocking system.
• A suitable expandable PLC with programming & 7” colour touch screen HMI.
• The Pharma grade silicon tubes are used for filling & CIP/SIP.
• There is a very less product change over time due to very less usage of mechanical parts.
• All liquid contact parts easily removable for cleaning and sterilization purpose.
• Machine with LAF which can maintain class 100 condition (OPTIONAL).
• Co eccentric nozzles for quick filling of liquids.
• For different heights of syringes, the whole assembly can be moved upwards & downwards.
• Production counter is given with password protection for daily track report.
• The faults can be detected on the PLC touch screen HMI and can be attended easily.
• The output speed can be appeared on HMI screen.
• Very less mechanical adjustment required due to the special design.
• User friendly and very less maintenance required.
• NITROGEN FLUSHING SYSTEM [OPTIONAL]: The filling unit has an inbuilt system for nitrogen flush. The unique dual
• filling nozzle flushes nitrogen before filling followed by filling operation.
• Most reliable & proven mechanical components such as pneumatics & CE certified electrical/electronic such as AC
• motor, AC Drives, PLC & HMI Touch screen, safety interlock & Sensors, MCB’s, relay etc.

The External Vial Washing Machine washes vials with minimal contact between machine parts and the vial. Our vial washing equipment effectively washes various sizes of vials with the assistance of changing parts.

Sample Products: Glass and Plastic Vials
Sample Product Size: 2 to 100 ml vials
Output Speed: up to 400 Products per minute

The Automatic Vial Filling Machine by Harikrushna Machines Pvt. Ltd. is designed to deliver precise, sterile, and high-speed filling of liquid products into pharmaceutical vials. It features a sturdy SS cabinet with safety acrylic covers, integrated laminar airflow, and a smooth Delrin slat conveyor for clean product handling. The peristaltic pump filling system ensures accurate and contamination-free dosing, while the vibrator bowl and chute provide efficient orientation and placement of 13 mm, 20 mm, and 32 mm rubber stoppers. Equipped with 4, 6, or 8 filling heads, the HMPL-PRE-VFB model handles vial sizes from 25 mm to 55 mm in diameter and filling volumes from 2 ml to 30 ml, achieving speeds of 30 to 400 vials per minute, depending on vial size and product characteristics. Controlled through an advanced electrical panel with AC Drive, PLC, and HMI, this machine ensures consistent performance and reliable aseptic processing for modern pharmaceutical production lines.