Harikrushna Machines Private Limited

Single Head Ampoule Filling and Sealing Machine, ensures precise and accurate dosing of pharmaceutical substances into each ampoule.

Similarly, This high-speed, automated machine guarantees uniformity and consistency in the filling, and the subsequent sealing process secures the contents.

The Automatic Ampoule Filling Sealing Machine by Harikrushna Machines Pvt. Ltd. (HMPL) ensures precise, sterile, and high-speed filling and sealing for glass ampoules used in pharmaceutical, veterinary, and biotech applications. Equipped with a Laminar Air Flow (LAF) System, the machine maintains a contamination-free environment throughout the process. Its multi-axis servo-driven technology controls the feed worm, infeed starwheels, ampoule travel rack, syringe dosing, nozzle diving, and ampoule cutting system, delivering unmatched accuracy and repeatability. Using imported rotary syringes, the system provides smooth, consistent filling and perfectly formed seals at speeds of up to 400 ampoules per minute, making it an ideal solution for modern high-efficiency sterile manufacturing lines.

Pre-Filled Syringe Packaging Line Consist of Pre-Filled Syringe Filling, Pre-Filled Syringe Stoppering, Pre-Filled Syringe Rod Inserting, and a Pre-Filled Syringe Sticker Labeling Machine.

Injection Vial Sealing Machine consists of the main structure covered with SS cabinet safety polycarbonate glass doors, Delrin slate conveyor, vials height adjustment screw, centralized lubrication system, out-feed turntable, vibrator bowl & chute for cap, in-feed screw & star plate, sensors, electrical panel, AC Drive, PLC & HMI.

• Model: HMPL-PRE-RVS
• Output Speed: 30 to 120 Vials/Minute

Key Features:

• The machine is manufactured or developed accordance with GMP standards.
• The structure is made of MS and cladded with SS 304.
• Rigid vibration free construction for trouble free performance.
• The mechanical driven system of the whole machine is through foot mounted motor and gear box.
• The complete synchronized mechanism is designed on gears and chain.
• Totally synchronized PLC controlled system.
• The whole machine covered with cabinet of SS and polycarbonate glass doors.
• User friendly to adjust the different speed (vials/minute) with the help of HMI.
• The Real output speed (vials/minute) appear on HMI.
• Few change parts are required for different vials.
• Vials without bungs and no caps are detected by the sensors and give the alarm alert and machine stop itself.
• Daily production ratio, production counter is given with the password protection.
• There is a special designed vibrator bowl and chute with no cap sensors for continuous flow of the cap.
• The faults such as vials without bungs, no caps appear on the HMI and can be attended easily.
• Very less mechanical adjustment required due to the special design.
• PLC modes are user friendly and can be operated easily.
• User-friendly and very less maintenance required.
• The structure construction of machine is useful to mount laminar flow.
• Most reliable and proven components such as Festo/SMC make pneumatic and electrical/electronic such as Bonfiglioli/Motovario/Rotomotive make AC motor, Delta make Drives, Delta make PLC & HMI, LEUZE/BANNER/SICK make Sensors, MCB & relay “CE” certified.

Syring Filling Machine/ Pre-Filled Flush Syringe Filling and Capping Machine with Reverse System - Top/ Bottom Filling Technology with Leak Proof Cap Sealing System Fill 3 ml to 20 ml volume flush syringes with 80 to 120 syringes per minute.

The Single Head ROPP Cap Sealing Machine by Harikrushna Machines Pvt. Ltd. provides a reliable and efficient solution for sealing ROPP aluminum caps on 10 ml to 5000 ml Round Glass or PET bottles. The system features a sturdy main structure with adjustable height, a precision cap sealing head, and a stable bottle holding unit to ensure secure and consistent sealing with every cycle. Capable of achieving up to 20 bottles per minute depending on product size and manual handling, the HMPL-SEMI-RCS model is ideal for small to medium-scale production environments. Simple to operate and maintain, it delivers dependable sealing performance for 25 mm or 28 mm ROPP caps, ensuring product integrity and a professional, tamper-evident finish.

The Semi ROPP Cap Sealing Machine by Harikrushna Machines Pvt. Ltd. provides a reliable and efficient solution for sealing ROPP aluminum caps on 10 ml to 5000 ml Round Glass or PET bottles. The system features a sturdy main structure with adjustable height, a precision cap sealing head, and a stable bottle holding unit to ensure secure and consistent sealing with every cycle. Capable of achieving up to 20 bottles per minute depending on product size and manual handling, the HMPL-SEMI-RCS model is ideal for small to medium-scale production environments. Simple to operate and maintain, it delivers dependable sealing performance for 25 mm or 28 mm ROPP caps, ensuring product integrity and a professional, tamper-evident finish.

The ROPP Cap Sealing Machine by Harikrushna Machines Pvt. Ltd. delivers fast, precise, and reliable sealing for Glass and Plastic bottles ranging from 10 ml to 5000 ml. Designed with a smooth product transmission belt, adjustable guides, in-feed screw, and star plate, the machine ensures accurate bottle positioning for consistent sealing. Its vibratory bowl and cap chute efficiently orient and feed ROPP aluminum caps (22 & 25 mm / 25 & 28 mm) to the sealing heads, while the height adjustment screw allows quick setup for different bottle sizes. With a durable structure, optional safety acrylic cover, and a smart electrical panel with motor, sensors, and AC drive, the HMPL-RCS model delivers up to 120 bottles per minute, making it ideal for industries that demand secure, professional, and tamper-evident packaging.

The Syringe Filling Equipment consisting of the main structure covered polycarbonate cabinet and SS 304 pipe, laminar airflow, filling head with individual servo motor, out-feed collection tray, vacuum system, pneumatic components, and electrical panel, AC Drive, PLC & HMI. Syringe Filling Machine & Stoppering Machine loaded on Stainless Steel in-feed hopper. A prefilled syringe manufacturing process machine tray can directly be loaded onto the PFS machine. Duly filled & stoppered syringes delivered on outfeed collection tray without hand touch.

• Model: ACCUFILLCOMBO-PFS
• Output Speed: Up to 100 PFS per minute @ 1 ml
  (Output may vary based on nature of the filling substance and volume)

Key Features:

• The machine is manufactured or developed accordance with GMP standards.
• The structure is made of SS 304 or cladded with SS 304.
• Rigid vibration free construction for trouble free performance.
• Machine without-feed trays for collection of syringe tub.
• All contact parts SS 316L and non-contact parts are SS 304.
• Machine suitable for different syringe size with help of change part and depends on characteristic of liquid.
• Servo with syringes synchronized system for filling Accuracy.
• Filling volume set with touch screen HMI.
• Pneumatically controlled Stoppering mechanism.
• Very easy & accurate electronic based volume setting of different pre-fill syringes.
• Zero Dripping filling stations.
• Diving system with the design of timer belt and Stepper Motor/pneumatic Control which has no Vibration and very
• smooth kind of filling, filling material must be Fill Centrally in the Syringe.
• Design of Nozzles and adjustment of flow rate is very useful for filling with minimum Air Bubble / foaming in
• the Syringes.
• Low air machine stop sensor.
• LAF stop machine stop sensor.
• Door interlocking system.
• A suitable expandable PLC with programming & 7” colour touch screen HMI.
• The Pharma grade silicon tubes are used for filling & CIP/SIP.
• There is a very less product change over time due to very less usage of mechanical parts.
• All liquid contact parts easily removable for cleaning and sterilization purpose.
• Machine with LAF which can maintain class 100 condition (OPTIONAL).
• Co eccentric nozzles for quick filling of liquids.
• For different heights of syringes, the whole assembly can be moved upwards & downwards.
• Production counter is given with password protection for daily track report.
• The faults can be detected on the PLC touch screen HMI and can be attended easily.
• The output speed can be appeared on HMI screen.
• Very less mechanical adjustment required due to the special design.
• User friendly and very less maintenance required.
• NITROGEN FLUSHING SYSTEM [OPTIONAL]: The filling unit has an inbuilt system for nitrogen flush. The unique dual
• filling nozzle flushes nitrogen before filling followed by filling operation.
• Most reliable & proven mechanical components such as pneumatics & CE certified electrical/electronic such as AC
• motor, AC Drives, PLC & HMI Touch screen, safety interlock & Sensors, MCB’s, relay etc.

Harikrushna Machines Pvt. Ltd. (HMPL) proudly offers the Automatic Screw Cap Sealing Machine, a versatile solution for sealing screw-type caps on bottles, jars, and various container types. Designed for efficiency, this machine handles bottles ranging from 10 ml to 500 ml at an impressive output speed of 30 to 120 products per minute. Equipped with advanced features like a stainless steel structure, adjustable guide belts, and a vibratory bowl for precise cap feeding, it delivers reliable performance across industries such as pharmaceuticals, dairy, food, beverages, and more.
The machine’s operation ensures precision at every step. Bottles pass through an in-feed screw and star wheel before reaching the capping head, which efficiently seals screw caps sized 25 or 28 mm. A vibratory bowl and chute ensure seamless cap delivery, while the capping head tightens caps with unmatched accuracy. After sealing, the bottles move effortlessly to the next stage via a conveyor. HMPL's multi-head configurations, ranging from 1 to 8 heads, allow for customization based on production demands, ensuring a perfect fit for diverse packaging needs.
Crafted to meet stringent quality standards, this screw capping machine integrates cutting-edge technology with robust construction. Its adjustable conveyor height, user-friendly controls, and modular design enable easy operation and quick changeovers for different bottle shapes and cap sizes. By combining performance, adaptability, and precision, HMPL continues to exceed customer expectations, making the Automatic Rotary Screw Cap Sealing Machine a trusted choice for businesses aiming to optimize their packaging processes.

The Automatic Dry Syrup Powder Filling Machine by Harikrushna Machines Pvt. Ltd. (HMPL) is engineered to deliver accurate, clean, and efficient filling of Dry Syrup, Powder, and Granules into bottles of various shapes and sizes. Equipped with a Single-Track Twin Hopper system and a reliable Auger-based dosing mechanism, it ensures precise filling even for higher grammage powders, achieving speeds of up to 120 bottles per minute depending on fill volume, powder properties, and bottle size. All product-contact parts are made from SS316, Nylon, and HDPE, ensuring excellent hygiene and durability. The machine features a pneumatically operated bottle separator that eliminates the need for bottle change parts, while the integrated in-feed turntable ensures smooth, continuous bottle feeding. This system provides consistent performance, reduced wastage, and optimized productivity for pharmaceutical and nutraceutical powder filling applications.